![]() ![]() However, it is poorly suited to the effective removal of larger solutes, such as β 2-microglobulin, even when high-flux membranes are used because solute diffusion coefficients decrease rapidly with the increasing molecular size. Haemodialysis is based on the diffusive transport of solutes across a semipermeable membrane and is effective in removing small solutes, such as urea, and correcting electrolyte, acid–base and fluid imbalances. Haemodiafiltration, review, definition, safety INTRODUCTIONĬonventional haemodialysis is the most widely used therapy for the replacement of renal function. ![]() This is the first report of the expert group arising from that conference. A EUDIAL consensus conference was held in Paris on 13 October 2011 to revisit terminology, safety and efficacy of online HDF. The prevalence of online HDF-treated patients is steadily increasing in Europe, averaging 15%. ![]() Europe is the leader in the field, having introduced the concept of ultra-purity for water and dialysis fluids and with notified bodies of the European Community having certified water treatment systems and online HDF machines. Several reports suggest that those therapies potentially improve the outcomes for end-stage renal disease patients. Given the increasing interest in convective therapies, the Working Group has started by focusing on haemodiafiltration (HDF) therapies. The general objective assigned to the EUropean DIALlysis (EUDIAL) Working Group by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) was to enhance the quality of dialysis therapies in Europe in the broadest possible sense. ![]()
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